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sulforaphane and (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid

sulforaphane has been researched along with (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baird, L; Bertrand, HC; Dinkova-Kostova, AT; Fowkes, A; Georgakopoulos, ND; Kachi, H; Schaap, M; Thiollier, C; Wells, G1
Aguayo-Orozco, A; Bach, A; Baig, A; Carmona, RMC; Garcia, AD; Narayanan, D; Pallesen, JS; Solbak, SMØ; Tran, KT; Zang, J1
Aleksunes, LM; Hu, L; Joy, MS; Thorne, G; Wen, X1

Other Studies

3 other study(ies) available for sulforaphane and (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid

ArticleYear
Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction.
    Journal of medicinal chemistry, 2015, Sep-24, Volume: 58, Issue:18

    Topics: Cell Line, Tumor; Click Chemistry; Computer Simulation; Databases, Chemical; Dose-Response Relationship, Drug; Fluorescence Polarization; HEK293 Cells; Heme Oxygenase-1; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Molecular Docking Simulation; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Protein Binding; Structure-Activity Relationship; Sulfoxides; Triazoles

2015
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Kelch-Like ECH-Associated Protein 1; Models, Molecular; Molecular Structure; NF-E2-Related Factor 2; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship; Surface Plasmon Resonance

2019
Activation of NRF2 Signaling in HEK293 Cells by a First-in-Class Direct KEAP1-NRF2 Inhibitor.
    Journal of biochemical and molecular toxicology, 2015, Volume: 29, Issue:6

    Topics: Active Transport, Cell Nucleus; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Gene Expression; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Phthalimides; Signal Transduction; Sulfoxides

2015